The Project Gutenberg eBook, A Letter on Suspended Animation, by Henry Hickman This eBook is for the use of anyone anywhere in the United States and most other parts of the world at no cost and with almost no restrictions whatsoever. You may copy it, give it away or re-use it under the terms of the Project Gutenberg License included with this eBook or online at www.gutenberg.org. If you are not located in the United States, you'll have to check the laws of the country where you are located before using this ebook. Title: A Letter on Suspended Animation containing experiments shewing that it may be safely employed during operations on animals Author: Henry Hickman Release Date: October 10, 2018 [eBook #58071] Language: English Character set encoding: UTF-8 ***START OF THE PROJECT GUTENBERG EBOOK A LETTER ON SUSPENDED ANIMATION*** Transcribed from the 1824 Office of W. Smith edition by David Price, email ccx074@pglaf.org [Picture: Pamphlet cover] A LETTER ON SUSPENDED ANIMATION, CONTAINING EXPERIMENTS _Shewing that it may be safely employed during_ OPERATIONS ON ANIMALS, With the View of ascertaining ITS PROBABLE UTILITY IN SURGICAL OPERATIONS ON THE Human Subject, _Addressed to_ T. A. KNIGHT, ESQ. OF DOWNTON CASTLE, Herefordshire, ONE OF THE PRESIDENTS OF THE ROYAL SOCIETY. * * * * * BY DR. H. HICKMAN, OF SHIFFNAL; Member of the Royal Medical Societies of Edinburgh, and of the Royal College of Surgeons, London. * * * * * IRONBRIDGE: Printed at the Office of W. Smith. 1824. _TO THE PUBLIC_. AT the particular request of gentlemen of the first rate talent, and who rank high in the scientific world, it is, that the author of the following letter is induced to lay it before the public generally, but more particularly his medical brethren; in the hope that some one or other, may be more fortunate in reducing the object of it beyond a possibility of doubt. It may be said, and with truth, that publications are too frequently the vehicles of self-adulation, and as such, suffer greatly from the lash of severe criticism; but the author begs to assure his readers, that his views are totally different, merely considering it a duty incumbent on him, (as a medical practitioner, and servant to the public), to make known any thing which has not been tried, and which ultimately may add something towards the relief of human suffering, arising from acute disease. The only method of obtaining this end, is, in the author’s opinion, candid discussion, and liberality of sentiment, which, too commonly is a deficient ingredient in the welfare of so important a profession, productive of serious consequences, not only to the parties themselves, but to the patient whose life is entrusted to their care. The duty and object, however, of the Physician and Surgeon, is generally considered to be the relief of a fellow-creature, by applying certain remedies to the cure of internal affections, or cutting some portion of the body, whereby parts are severed from each other altogether, or relieving cavities of the aggravating cause of disease. There is not an individual, he believes, who does not shudder at the idea of an operation, however skilful the Surgeon, or urgent the case, knowing the great pain that must necessarily be endured; and it is frequently lamented by the operator himself, that something has not been done to tranquilize fear, and diminish the agony of the patient. With this view of the subject then, it is, that he submits his observations and experiments to the public in the brief form of a letter to a private gentleman of the highest talent as a man of science, who with others, thought them worthy to be laid before the Royal Society; and if one grain of knowledge can be added to the general fund, to obtain a means for the relief of pain, the labours of the author will be amply rewarded. A LETTER, &c. _Sir_, THE facility of suspending animation, by carbonic acid gas, and other means, without permanent injury to the subject, having been long known, it appears to me rather singular that no experiments have hitherto been made with the object of ascertaining whether operations could be successfully performed upon animals whilst in a torpid state; and whether wounds inflicted upon them in such a state would be found to heal with greater or less facility than similar wounds inflicted on the same animals whilst in possession of all their powers of feeling and suffering. Several circumstances led me to suspect that wounds made on animals whilst in a torpid state, would be found, in many cases, to heal most readily; and the results of some experiments which I have made, lead me to think that these conjectures are well founded, and to hope that you will think the results sufficiently interesting to induce you to do me the honor to lay them before the Royal Society. The experiments were necessarily made upon living animals, but they were confined to animals previously condemned to death; and as their lives were preserved, and their suffering very slight, (certainly not so great as they would have sustained if their lives had been taken away by any of the ordinary methods of killing such animals) I venture to hope that they, in the aggregate, rather received benefit than injury. Subjects of different species were employed, chiefly puppies of a few weeks or months old, and the experiments were often repeated, but as the results were all uniform, and as my chief object is to attract the attention of other medical men to the subject, I wish to do little more than state the general results. EXPERIMENT 1st. Dogs of about a month old were placed under a glass cover, surrounded by water, so as to prevent the ingress of atmospheric air, where their respiration in a short time ceased, and a part of one ear of each was then taken off; there was no hemorrhage, and the wounds were healed at the end of the third day, without any inflammation having taken place, or the Animals having apparently suffered any pain or inconvenience from the operation. EXPERIMENT 2d. After the same animals had fully recovered their powers of feeling, a similar part of the other ear of each was taken off; a good deal of blood now flowed from the wounds, and some degree of inflammation followed, and the wounds did not heal till the fifth day. EXPERIMENT 3d. An experiment was made similar to No. 1, in every respect, except that the suspension of animation was much more suddenly brought on by the agency of sulphuric acid and carbonate of Lime. The results in this case were not so satisfactory; some blood escaped from the wounds, and a slight degree of inflammation followed, and the wounds did not heal so rapidly as the first experiment. EXPERIMENT 4th. Mice, having been confined in a glass tube of a foot long, were rendered insensible by carbonic acid gas slowly introduced in small quantities, and one foot from each was taken off; no hemorrhage took place upon the return of sensation, and the wounds appeared quite healed on the third day, without the animals having apparently suffered pain, when they were given their liberty. EXPERIMENT 5th. An adult dog was rendered insensible by means similar to the preceding, and the muscles and blood-vessels of one of its legs were divided. There was no hemorrhage from the smaller vessels; a ligature which secured the main artery came away on the fourth day, and the animal recovered without having at any period shewn any material symptom of uneasiness. In this experiment animation was suspended during seventeen minutes, allowing respiration occasionally to intervene by means of inflating instruments. EXPERIMENT 6th. A dog was rendered insensible by the means employed in experiment first, and an incision was made through the muscles of the loin, through which a ligature was passed, and made tight; no appearance whatever of suffering occurred upon the return of animation, nor till the following day, when inflammation came on with subsequent suppuration. The ligature came away on the seventh day, and on the twelfth the wound was healed. * * * * * As the recital of such experiments as those preceding must be as little agreeable to you, as the repetition of them has been to myself, I shall not give a detail of any others, but shall only state the opinions which the aggregate results have led me to entertain. I feel perfectly satisfied that any surgical operation might be performed with quite as much safety upon a subject in an insensible state, as in a sensible state, and that a patient might be kept with perfect safety long enough in an insensible state, for the performance of the most tedious operation. My own experience has also satisfied me that in very many cases the best effects would be produced by the patient’s mind being relieved from the anticipation of suffering, and his body from the actual suffering of a severe operation; and I believe that there are few, if any Surgeons, who could not operate more skillfully when they were conscious they were not inflicting pain. There are also many cases in which it would be important to prevent any considerable hemorrhage, and in which the surgeon would feel the advantages of a diminished flow of blood during an operation. I have reason to believe that no injurious consequence would follow if the necessity of the case should call for more than once suspension of animation; for a young growing dog was several times rendered insensible by carbonic acid gas, with intervals of about twenty-four or forty-eight hours, without sustaining, apparently, the slightest injury. Its appetite continued perfectly good, and I ascertained, by weighing it, that it gained weight rapidly. I am not, at present, aware of any source of danger to a patient, from an operation performed during a state of insensibility, which would not operate to the same extent upon a patient in full possession of his powers of suffering, particularly if he were rendered insensible by being simply subjected to respire confined air. I used inflating instruments in one experiment only, and therefore am not prepared to say to what extent such may be used with advantage; but I think it probable that those and the Galvanic fluid would operate in restoring animation in some cases. I was prepared to employ the Galvanic fluid if any case had occurred to render the operation of any stimulant necessary, but all the subjects recovered by being simply exposed to the open air; and I feel so confident that animation in the human subject could be safely suspended by proper means, carefully employed, that, (although I could not conscientiously recommend a patient to risk his life in the experiment,) I certainly should not hesitate a moment to become the subject of it, if I were under the necessity of suffering any long or severe operation, _I remain_, _Sir_, _Your obedient Servant_, H. H. HICKMAN. _Shifnal_, _Aug._ 14_th_, 1824. * * * * * FINIS. ***END OF THE PROJECT GUTENBERG EBOOK A LETTER ON SUSPENDED ANIMATION*** ******* This file should be named 58071-0.txt or 58071-0.zip ******* This and all associated files of various formats will be found in: http://www.gutenberg.org/dirs/5/8/0/7/58071 Updated editions will replace the previous one--the old editions will be renamed. Creating the works from print editions not protected by U.S. copyright law means that no one owns a United States copyright in these works, so the Foundation (and you!) can copy and distribute it in the United States without permission and without paying copyright royalties. Special rules, set forth in the General Terms of Use part of this license, apply to copying and distributing Project Gutenberg-tm electronic works to protect the PROJECT GUTENBERG-tm concept and trademark. Project Gutenberg is a registered trademark, and may not be used if you charge for the eBooks, unless you receive specific permission. If you do not charge anything for copies of this eBook, complying with the rules is very easy. You may use this eBook for nearly any purpose such as creation of derivative works, reports, performances and research. They may be modified and printed and given away--you may do practically ANYTHING in the United States with eBooks not protected by U.S. copyright law. Redistribution is subject to the trademark license, especially commercial redistribution. START: FULL LICENSE THE FULL PROJECT GUTENBERG LICENSE PLEASE READ THIS BEFORE YOU DISTRIBUTE OR USE THIS WORK To protect the Project Gutenberg-tm mission of promoting the free distribution of electronic works, by using or distributing this work (or any other work associated in any way with the phrase "Project Gutenberg"), you agree to comply with all the terms of the Full Project Gutenberg-tm License available with this file or online at www.gutenberg.org/license. Section 1. General Terms of Use and Redistributing Project Gutenberg-tm electronic works 1.A. By reading or using any part of this Project Gutenberg-tm electronic work, you indicate that you have read, understand, agree to and accept all the terms of this license and intellectual property (trademark/copyright) agreement. If you do not agree to abide by all the terms of this agreement, you must cease using and return or destroy all copies of Project Gutenberg-tm electronic works in your possession. If you paid a fee for obtaining a copy of or access to a Project Gutenberg-tm electronic work and you do not agree to be bound by the terms of this agreement, you may obtain a refund from the person or entity to whom you paid the fee as set forth in paragraph 1.E.8. 1.B. "Project Gutenberg" is a registered trademark. It may only be used on or associated in any way with an electronic work by people who agree to be bound by the terms of this agreement. There are a few things that you can do with most Project Gutenberg-tm electronic works even without complying with the full terms of this agreement. See paragraph 1.C below. There are a lot of things you can do with Project Gutenberg-tm electronic works if you follow the terms of this agreement and help preserve free future access to Project Gutenberg-tm electronic works. See paragraph 1.E below. 1.C. The Project Gutenberg Literary Archive Foundation ("the Foundation" or PGLAF), owns a compilation copyright in the collection of Project Gutenberg-tm electronic works. Nearly all the individual works in the collection are in the public domain in the United States. If an individual work is unprotected by copyright law in the United States and you are located in the United States, we do not claim a right to prevent you from copying, distributing, performing, displaying or creating derivative works based on the work as long as all references to Project Gutenberg are removed. Of course, we hope that you will support the Project Gutenberg-tm mission of promoting free access to electronic works by freely sharing Project Gutenberg-tm works in compliance with the terms of this agreement for keeping the Project Gutenberg-tm name associated with the work. You can easily comply with the terms of this agreement by keeping this work in the same format with its attached full Project Gutenberg-tm License when you share it without charge with others. 1.D. The copyright laws of the place where you are located also govern what you can do with this work. Copyright laws in most countries are in a constant state of change. If you are outside the United States, check the laws of your country in addition to the terms of this agreement before downloading, copying, displaying, performing, distributing or creating derivative works based on this work or any other Project Gutenberg-tm work. The Foundation makes no representations concerning the copyright status of any work in any country outside the United States. 1.E. Unless you have removed all references to Project Gutenberg: 1.E.1. The following sentence, with active links to, or other immediate access to, the full Project Gutenberg-tm License must appear prominently whenever any copy of a Project Gutenberg-tm work (any work on which the phrase "Project Gutenberg" appears, or with which the phrase "Project Gutenberg" is associated) is accessed, displayed, performed, viewed, copied or distributed: This eBook is for the use of anyone anywhere in the United States and most other parts of the world at no cost and with almost no restrictions whatsoever. You may copy it, give it away or re-use it under the terms of the Project Gutenberg License included with this eBook or online at www.gutenberg.org. If you are not located in the United States, you'll have to check the laws of the country where you are located before using this ebook. 1.E.2. If an individual Project Gutenberg-tm electronic work is derived from texts not protected by U.S. copyright law (does not contain a notice indicating that it is posted with permission of the copyright holder), the work can be copied and distributed to anyone in the United States without paying any fees or charges. If you are redistributing or providing access to a work with the phrase "Project Gutenberg" associated with or appearing on the work, you must comply either with the requirements of paragraphs 1.E.1 through 1.E.7 or obtain permission for the use of the work and the Project Gutenberg-tm trademark as set forth in paragraphs 1.E.8 or 1.E.9. 1.E.3. If an individual Project Gutenberg-tm electronic work is posted with the permission of the copyright holder, your use and distribution must comply with both paragraphs 1.E.1 through 1.E.7 and any additional terms imposed by the copyright holder. Additional terms will be linked to the Project Gutenberg-tm License for all works posted with the permission of the copyright holder found at the beginning of this work. 1.E.4. Do not unlink or detach or remove the full Project Gutenberg-tm License terms from this work, or any files containing a part of this work or any other work associated with Project Gutenberg-tm. 1.E.5. Do not copy, display, perform, distribute or redistribute this electronic work, or any part of this electronic work, without prominently displaying the sentence set forth in paragraph 1.E.1 with active links or immediate access to the full terms of the Project Gutenberg-tm License. 1.E.6. You may convert to and distribute this work in any binary, compressed, marked up, nonproprietary or proprietary form, including any word processing or hypertext form. However, if you provide access to or distribute copies of a Project Gutenberg-tm work in a format other than "Plain Vanilla ASCII" or other format used in the official version posted on the official Project Gutenberg-tm web site (www.gutenberg.org), you must, at no additional cost, fee or expense to the user, provide a copy, a means of exporting a copy, or a means of obtaining a copy upon request, of the work in its original "Plain Vanilla ASCII" or other form. Any alternate format must include the full Project Gutenberg-tm License as specified in paragraph 1.E.1. 1.E.7. Do not charge a fee for access to, viewing, displaying, performing, copying or distributing any Project Gutenberg-tm works unless you comply with paragraph 1.E.8 or 1.E.9. 1.E.8. You may charge a reasonable fee for copies of or providing access to or distributing Project Gutenberg-tm electronic works provided that * You pay a royalty fee of 20% of the gross profits you derive from the use of Project Gutenberg-tm works calculated using the method you already use to calculate your applicable taxes. The fee is owed to the owner of the Project Gutenberg-tm trademark, but he has agreed to donate royalties under this paragraph to the Project Gutenberg Literary Archive Foundation. Royalty payments must be paid within 60 days following each date on which you prepare (or are legally required to prepare) your periodic tax returns. Royalty payments should be clearly marked as such and sent to the Project Gutenberg Literary Archive Foundation at the address specified in Section 4, "Information about donations to the Project Gutenberg Literary Archive Foundation." * You provide a full refund of any money paid by a user who notifies you in writing (or by e-mail) within 30 days of receipt that s/he does not agree to the terms of the full Project Gutenberg-tm License. You must require such a user to return or destroy all copies of the works possessed in a physical medium and discontinue all use of and all access to other copies of Project Gutenberg-tm works. * You provide, in accordance with paragraph 1.F.3, a full refund of any money paid for a work or a replacement copy, if a defect in the electronic work is discovered and reported to you within 90 days of receipt of the work. * You comply with all other terms of this agreement for free distribution of Project Gutenberg-tm works. 1.E.9. If you wish to charge a fee or distribute a Project Gutenberg-tm electronic work or group of works on different terms than are set forth in this agreement, you must obtain permission in writing from both the Project Gutenberg Literary Archive Foundation and The Project Gutenberg Trademark LLC, the owner of the Project Gutenberg-tm trademark. Contact the Foundation as set forth in Section 3 below. 1.F. 1.F.1. Project Gutenberg volunteers and employees expend considerable effort to identify, do copyright research on, transcribe and proofread works not protected by U.S. copyright law in creating the Project Gutenberg-tm collection. Despite these efforts, Project Gutenberg-tm electronic works, and the medium on which they may be stored, may contain "Defects," such as, but not limited to, incomplete, inaccurate or corrupt data, transcription errors, a copyright or other intellectual property infringement, a defective or damaged disk or other medium, a computer virus, or computer codes that damage or cannot be read by your equipment. 1.F.2. LIMITED WARRANTY, DISCLAIMER OF DAMAGES - Except for the "Right of Replacement or Refund" described in paragraph 1.F.3, the Project Gutenberg Literary Archive Foundation, the owner of the Project Gutenberg-tm trademark, and any other party distributing a Project Gutenberg-tm electronic work under this agreement, disclaim all liability to you for damages, costs and expenses, including legal fees. YOU AGREE THAT YOU HAVE NO REMEDIES FOR NEGLIGENCE, STRICT LIABILITY, BREACH OF WARRANTY OR BREACH OF CONTRACT EXCEPT THOSE PROVIDED IN PARAGRAPH 1.F.3. YOU AGREE THAT THE FOUNDATION, THE TRADEMARK OWNER, AND ANY DISTRIBUTOR UNDER THIS AGREEMENT WILL NOT BE LIABLE TO YOU FOR ACTUAL, DIRECT, INDIRECT, CONSEQUENTIAL, PUNITIVE OR INCIDENTAL DAMAGES EVEN IF YOU GIVE NOTICE OF THE POSSIBILITY OF SUCH DAMAGE. 1.F.3. LIMITED RIGHT OF REPLACEMENT OR REFUND - If you discover a defect in this electronic work within 90 days of receiving it, you can receive a refund of the money (if any) you paid for it by sending a written explanation to the person you received the work from. If you received the work on a physical medium, you must return the medium with your written explanation. The person or entity that provided you with the defective work may elect to provide a replacement copy in lieu of a refund. If you received the work electronically, the person or entity providing it to you may choose to give you a second opportunity to receive the work electronically in lieu of a refund. If the second copy is also defective, you may demand a refund in writing without further opportunities to fix the problem. 1.F.4. Except for the limited right of replacement or refund set forth in paragraph 1.F.3, this work is provided to you 'AS-IS', WITH NO OTHER WARRANTIES OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PURPOSE. 1.F.5. Some states do not allow disclaimers of certain implied warranties or the exclusion or limitation of certain types of damages. If any disclaimer or limitation set forth in this agreement violates the law of the state applicable to this agreement, the agreement shall be interpreted to make the maximum disclaimer or limitation permitted by the applicable state law. The invalidity or unenforceability of any provision of this agreement shall not void the remaining provisions. 1.F.6. INDEMNITY - You agree to indemnify and hold the Foundation, the trademark owner, any agent or employee of the Foundation, anyone providing copies of Project Gutenberg-tm electronic works in accordance with this agreement, and any volunteers associated with the production, promotion and distribution of Project Gutenberg-tm electronic works, harmless from all liability, costs and expenses, including legal fees, that arise directly or indirectly from any of the following which you do or cause to occur: (a) distribution of this or any Project Gutenberg-tm work, (b) alteration, modification, or additions or deletions to any Project Gutenberg-tm work, and (c) any Defect you cause. Section 2. Information about the Mission of Project Gutenberg-tm Project Gutenberg-tm is synonymous with the free distribution of electronic works in formats readable by the widest variety of computers including obsolete, old, middle-aged and new computers. It exists because of the efforts of hundreds of volunteers and donations from people in all walks of life. Volunteers and financial support to provide volunteers with the assistance they need are critical to reaching Project Gutenberg-tm's goals and ensuring that the Project Gutenberg-tm collection will remain freely available for generations to come. In 2001, the Project Gutenberg Literary Archive Foundation was created to provide a secure and permanent future for Project Gutenberg-tm and future generations. To learn more about the Project Gutenberg Literary Archive Foundation and how your efforts and donations can help, see Sections 3 and 4 and the Foundation information page at www.gutenberg.org Section 3. Information about the Project Gutenberg Literary Archive Foundation The Project Gutenberg Literary Archive Foundation is a non profit 501(c)(3) educational corporation organized under the laws of the state of Mississippi and granted tax exempt status by the Internal Revenue Service. The Foundation's EIN or federal tax identification number is 64-6221541. Contributions to the Project Gutenberg Literary Archive Foundation are tax deductible to the full extent permitted by U.S. federal laws and your state's laws. The Foundation's principal office is in Fairbanks, Alaska, with the mailing address: PO Box 750175, Fairbanks, AK 99775, but its volunteers and employees are scattered throughout numerous locations. Its business office is located at 809 North 1500 West, Salt Lake City, UT 84116, (801) 596-1887. Email contact links and up to date contact information can be found at the Foundation's web site and official page at www.gutenberg.org/contact For additional contact information: Dr. Gregory B. Newby Chief Executive and Director gbnewby@pglaf.org Section 4. Information about Donations to the Project Gutenberg Literary Archive Foundation Project Gutenberg-tm depends upon and cannot survive without wide spread public support and donations to carry out its mission of increasing the number of public domain and licensed works that can be freely distributed in machine readable form accessible by the widest array of equipment including outdated equipment. Many small donations ($1 to $5,000) are particularly important to maintaining tax exempt status with the IRS. The Foundation is committed to complying with the laws regulating charities and charitable donations in all 50 states of the United States. Compliance requirements are not uniform and it takes a considerable effort, much paperwork and many fees to meet and keep up with these requirements. We do not solicit donations in locations where we have not received written confirmation of compliance. To SEND DONATIONS or determine the status of compliance for any particular state visit www.gutenberg.org/donate While we cannot and do not solicit contributions from states where we have not met the solicitation requirements, we know of no prohibition against accepting unsolicited donations from donors in such states who approach us with offers to donate. International donations are gratefully accepted, but we cannot make any statements concerning tax treatment of donations received from outside the United States. U.S. laws alone swamp our small staff. Please check the Project Gutenberg Web pages for current donation methods and addresses. Donations are accepted in a number of other ways including checks, online payments and credit card donations. To donate, please visit: www.gutenberg.org/donate Section 5. General Information About Project Gutenberg-tm electronic works. Professor Michael S. Hart was the originator of the Project Gutenberg-tm concept of a library of electronic works that could be freely shared with anyone. For forty years, he produced and distributed Project Gutenberg-tm eBooks with only a loose network of volunteer support. Project Gutenberg-tm eBooks are often created from several printed editions, all of which are confirmed as not protected by copyright in the U.S. unless a copyright notice is included. Thus, we do not necessarily keep eBooks in compliance with any particular paper edition. Most people start at our Web site which has the main PG search facility: www.gutenberg.org This Web site includes information about Project Gutenberg-tm, including how to make donations to the Project Gutenberg Literary Archive Foundation, how to help produce our new eBooks, and how to subscribe to our email newsletter to hear about new eBooks.